Adelmidrol (1675-66-7) Olupese - Cofttek

Adelmidrol (1675-66-7)

June 29, 2022

Cofttek jẹ olupese Adelmidrol (1675-66-7) ti o dara julọ ni Ilu China. Ile-iṣẹ wa ni eto iṣakoso iṣelọpọ pipe (ISO9001 & ISO14001), pẹlu agbara iṣelọpọ oṣooṣu ti 260kg.


ipo: Ni Ifilelẹ Production
Apapọ: 1kg / apo, 25kg / Ilu

Adelmidrol Sawọn ilana

Name: Adelmidrol
CAS: 1675-66-7
ti nw 98%
Agbekalẹ molula C13H26N2O4
Iwuwo molula: 274.36 g / mol
Nkan aaye: 132-134 ºC
Orukọ kemikali: N, N'-Bis (2-hydroxyethyl) nonanediamide
Synonyms: Adelmidrol 1675-66-7 N,N'-bis(2-hydroxyethyl)nonanediamide AdelMitrol UNII-1BUC3685QU Die e sii…
InChI Key: PAHZPHDAJQIETD-UHFFFAOYSA-N
Igbesi aye Aitẹnilọrun: N / A
Solubility: Tiotuka ninu omi; Ethanol; DMSO
Ipo Ibi ipamọ: 0 - 4 C fun igba kukuru (awọn ọjọ si awọn ọsẹ), tabi -20 C fun igba pipẹ (awọn oṣu)
ohun elo: O ti lo lọpọlọpọ ni Ilu Italia ni oogun ti ogbo lati tọju iredodo awọ ara. Ni ọdun 2015, a rii pe agbo-ara naa tun ṣe iṣe ipa-iredodo ti a fun ni eto ni 10 miligiramu fun iwuwo ara kg.
irisi: White lulú

 

Kini Adelmidrol (1675-66-7)?

Adelmidrol jẹ itọsẹ diehanolamide semisynthetic ti azelaic acid, ati pe o ni ilana kemikali alamimọ. O pin si bi amide, ati pe o jọra si palmitoylethanolamide, moleku obi ni kilasi ALIAmide ti awọn oogun. ALIAmides jẹ ẹgbẹ ti awọn itọsẹ acid fatty pẹlu awọn ohun-ini cannabimimetic eyiti o ni egboogi-iredodo ati awọn ipa analgesic ati pe a ro pe o ṣiṣẹ nipa idinku imuṣiṣẹ sẹẹli mast. Adelmidrol jẹ itọsẹ ethanolamide egboogi-iredodo ti azelaic acid.

 

Adelmidrol (1675-66-7) anfani

Adelmidrol jẹ itọsẹ sintetiki ti azelaic acid, dicarboxylic acid ti o kunju ti o nwaye nipa ti ara, ti o wa ni diẹ ninu awọn irugbin odidi ati ni awọn iye to wa ninu ara eniyan. Kemikali, ademidrol jẹ N, N-bis (2-hydroxyethyl) ti kii ṣe anediamide ati pe o jẹ ẹya amphiphilic tabi apapọ amphipathic, ti o ni awọn ohun-ini hydrophilic mejeeji ati hydrophobic, ti o ṣe ojurere solubility mejeeji ni olomi ati media Organic. Adelmidrol jẹ ti idile aliamide, ẹgbẹ kan ti awọn itọsẹ acid ọra pẹlu awọn ohun-ini cannabimimetic, ni anfani lati ṣakoso hyperreactivity sẹẹli mast (MC) ni ọpọlọpọ awọn pathophysiological ati awọn ipo iṣan. Ọna NF-κB Pro-inflammatory ti dinku ni pataki nipasẹ itọju pẹlu adelmidrol. Ipa egboogi-iredodo ti adelmidrol farahan lati ni ibatan lori imuṣiṣẹ PPAR-gamma. Adelmidrol jẹ doko ni oke fun awọn rudurudu awọ iredodo eniyan ati pe o ni anfani lati ṣe iyipada esi iredodo ni keratinocytes eniyan. Apapọ hyaluronic acid ati adelmidrol ṣe ilọsiwaju awọn ami ti osteoarthritis ti o fa nipasẹ monosodium iodoacetate.

 

Adelmidrol (1675-66-7) ohun elo?

Adelmidrol jẹ itọsẹ semisynthetic ti azelaic acid ati afọwọṣe ti agbo anti-iredodo palmitoylethanolamide (PEA), aliamide ati ọmọ ẹgbẹ ti idile ti fatty acid amide ifihan awọn ohun elo pẹlu awọn ohun-ini cannabimimetic. Awọn ipa-egbogi-iredodo ati awọn ipa antinociceptive ti aliamides PEA ati adelmidrol ni a ti ṣe afihan ni ọpọlọpọ awọn ẹkọ-iṣaaju iṣaaju, mejeeji ni vitro ati ni vivo. Awọn iṣe wọn ni a ro pe o jẹ nitori, o kere ju ni apakan, si agbara wọn lati ṣe atunṣe-ṣiṣẹsẹhin sẹẹli mast ati itusilẹ olulaja sẹẹli mast ni awọn ipo iṣan-ara ati awọn arun aisan.

 

Adelmidrol lulú fun sale(Nibo lati Ra Adelmidrol lulú ni olopobobo)

Ile-iṣẹ wa gbadun awọn ibatan igba pipẹ pẹlu awọn alabara wa nitori a fojusi iṣẹ iṣẹ alabara ati pese awọn ọja nla. Ti o ba nifẹ si ọja wa, a rọ pẹlu isọdi ti awọn aṣẹ lati baamu iwulo rẹ pato ati akoko akoko iyara wa lori awọn iṣeduro awọn iṣeduro iwọ yoo ni itọwo ọja wa ni akoko gidi. A tun idojukọ lori awọn iṣẹ kun-iye. A wa fun awọn ibeere iṣẹ ati alaye lati ṣe atilẹyin iṣowo rẹ.

A jẹ olutaja Adelmidrol lulú alamọdaju fun awọn ọdun pupọ, a pese awọn ọja pẹlu idiyele ifigagbaga, ati pe ọja wa jẹ didara ti o ga julọ ati pe o wa ni muna, idanwo ominira lati rii daju pe o jẹ ailewu fun lilo ni ayika agbaye.

 

jo

  1. Cerrato, Santiago; Brazil, Pilar; della Valle, Maria Federica; Miolo, Alda; Puigdemont, Anna (2012). "Ipa idalọwọduro ti Adelmidrol ti agbegbe lori antigen-induced skin whal ati ihuwasi sẹẹli mast ni awoṣe ireke ti dermatitis aleji”. BMC Veterinary Iwadi. 8 (1): 230. doi: 10.1186 / 1746-6148-8-230. PMC 3540011. PMID 23181761.
  2. Cordaro, M; Impellizzeri, D; Gugliandolo, E; Siracusa, R; Crupi, R; Esposito, E; Cuzzocrea, S (2016). "Adelmidrol, Palmitoylethanolamide Analogue, gẹgẹbi Itọju Ẹjẹ Titun Titun fun Itọju Arun Ifun Ifun". Molecular Pharmacology. 90 (5): 549–561. doi:10.1124/mol.116.105668. PMID 27625036.
  3. Abramo, F; Salluzzi, D; Leotta, R; Auxili, S; Nólì, C; Miolo, A; Mantis, P; Lloyd, D. H (2008). “Mofometry sẹẹli mast ati densitometry ni awọn ọgbẹ awọ idanwo ti a tọju pẹlu jeli ti o ni adelmidrol: Iwadii iṣakoso ibibo”. Awọn ọgbẹ : Akopọ ti Iwadi Ile-iwosan ati Iṣeṣe. 20 (6): 149–57. PMID 25942520.

 


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