Iṣuu soda Citicoline (CDP Choline soda)(33818-15-4) Sawọn ilana
| Name: | Iṣuu soda Citicoline (CDP Choline soda) |
| CAS: | 33818-15-4 |
| ti nw | 98% |
| Agbekalẹ molula | C14H25N4NaO11P2 |
| Iwuwo molula: | 510.308 g / mol |
| Orisun Isanmi: | > 240 ° C |
| Orukọ kemikali: | Sodium Citicoline; Iṣuu soda Cdp-choline |
| Synonyms: | Sodium [[(2S,3R,4S,5S)-5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl]2-(trimethylazaniumyl)ethyl phosphate |
| InChI Key: | YWAFNFGRBBSPD-KDVMHAGBSA-M |
| Igbesi aye Aitẹnilọrun: | 56 wakati |
| Solubility: | Wahala ni DMSO, Omi (Kekere) |
| Ipo Ibi ipamọ: | Gbẹ, okunkun ati ni 0 - 4 C fun igba kukuru (awọn ọjọ si awọn ọsẹ) tabi -20 C fun igba pipẹ (awọn oṣu si ọdun). |
| ohun elo: | Citicoline iṣuu soda jẹ aṣoju neuroprotective ati afikun afikun onje |
| irisi: | Funfun ti o mọ dulú |
Sodium Citicoline (33818-15-4) NMR julọ.Oniranran
Ti o ba nilo COA, MSDS, HNMR fun ipele kọọkan ti ọja ati alaye miiran, jọwọ kan si wa alakoso tita.
ohun ti o jẹ Iṣuu soda Citicoline (CDP Choline soda)(33818-15-4) ?
Citicoline Sodium (CDP-choline Sodium, cytidine 5'-diphosphocholine) lulú jẹ ohun elo ti o ni omi ti o ni iyọdajẹ ti o ṣiṣẹ gẹgẹbi iṣaju si choline mejeeji ati cytidine laarin ọpọlọ (eyiti o yipada si uridine). Si eniyan, Citicoline Sodium jẹ ounjẹ to ṣe pataki bi ipa rẹ ninu idinku eewu ti awọn abawọn tube ti iṣan, arun ẹdọ ọra, ati awọn ilana ilana miiran ti ni akọsilẹ. CDP-choline iṣuu soda jẹ ọkan ninu awọn phospholipids mẹta ti o ni choline ti o le jẹ afikun ẹnu (awọn meji miiran jẹ alpha-GPC ati phosphatidylcholine).
Iṣuu soda Citicoline (CDP Choline soda)(33818-15-4) anfani
CDP-choline n mu biosynthesis ti iṣelọpọ phospholipids ṣiṣẹ ninu awọn membranes ti iṣan, mu iṣelọpọ ti ọpọlọ pọ si ati awọn iṣe lori awọn ipele ti ọpọlọpọ awọn neurotransmitters. Nitorinaa, a ti fihan rẹ ni aṣeyẹwo pe CDP-choline n mu noradrenaline ati awọn ipele dopamine pọ si ni CNS.
Afikun yii jẹ itọju si ọna idilọwọ tabi atọju awọn ailagbara iranti ti o ni nkan ṣe pẹlu ti ogbo nitori otitọ pe mejeeji ti awọn ohun elo ti o funni jẹ neuroprotective ati o pọju mu eko. Lakoko ti o dabi pe o munadoko diẹ sii ju phosphatidylcholine (PC) ni ipa yii, ni apakan nitori tun npọ si iṣelọpọ PC ni ọpọlọ, agbara rẹ jẹ afiwera si ti Alpha-GPC.
Iṣuu soda Citicoline (CDP Choline soda)(33818-15-4) ipawo
CDP-choline ni diẹ ninu awọn lilo agbara miiran ni ibatan si idanimọ. O ti lo ni igbagbogbo bi imudara iranti ni ọdọ, ṣugbọn pelu diẹ ninu awọn iwadii ti o daba pe eyi ṣee ṣe pẹlu CDP-choline ti ẹnu, ko si awọn ẹkọ eniyan ni ọdọ ni aaye yii ni akoko. Iwadii kan ti ṣe akiyesi ilosoke ninu ifojusi pẹlu iwọn kekere CDP-choline (eyiti o nilo lati tun ṣe), ati CDP-choline le ni awọn ipa bi ẹya egboogi-afẹsodi ti o lodi si kokeni mejeeji ati (ẹri akọkọ ti o daba) ounjẹ bakanna ..
Iṣuu soda Citicoline (CDP Choline soda)(33818-15-4) ohun elo
Citicoline Sodium (CDP Choline Sodium) lulú jẹ oluranlowo neuroprotective. O n ṣiṣẹ nipa gbigbe ibaraẹnisọrọ sẹẹli pọ si, iwuri idapọ ti SAMe, ati jijẹ iṣelọpọ ti glucose pọ si. Iṣu lulú Citicoline Sodium (CDP Choline Sodium) lulú jẹ nucleotide ti n ṣẹlẹ nipa ti ara; agbedemeji ni ipa-ọna akọkọ ti lecitin biosynthesis. Neuroprotective. O ti lo ninu itọju ikọlu iṣan ara ati ibalokanjẹ ori. Neuroprotective ọja. Citicholine ṣe afihan awọn ipa aabo ni ischemia ti ọpọlọ, ọgbẹ ọpọlọ, ati awọn rudurudu iranti. Laipe fihan ipa lodi si iyawere nigbati a ba fun pẹlu AchEIs (Onidena Acetylcholinesterase). N ṣe afihan Neuroprotective, iṣẹ acnticonvulsant ati ipa imukuro ni iwọn lilo 150mg / kg ninu awọn eku. Afihan ti a fihan lodi si aiṣedede imoye ti a fa ni aluminiomu ninu awọn eku idinku ipele giluteni ti o ga, atẹgun atẹgun ati KO ṣe agbejade pupọ ni hippocampus.
Iṣuu soda Citicoline (CDP Choline soda)(33818-15-4) lulú fun sale
(Nibo ni lati Ra Iṣuu Citicoline (CDP Choline soda)(33818-15-4) lulú ni olopobo)
Ile-iṣẹ wa gbadun awọn ibatan igba pipẹ pẹlu awọn alabara wa nitori a dojukọ alabara iṣẹ ati pese awọn ọja nla. Ti o ba nifẹ si ọja wa, a ni irọrun pẹlu isọdi ti awọn ibere lati ba iwulo rẹ pato ati akoko itọsọna iyara wa lori awọn iṣeduro awọn iṣeduro pe iwọ yoo ni itọwo nla ọja wa ni akoko. A tun ṣe idojukọ awọn iṣẹ ti a fi kun iye. A wa fun awọn ibeere iṣẹ ati alaye lati ṣe atilẹyin iṣowo rẹ.
A jẹ ọjọgbọn kan Iṣuu soda Citicoline (CDP Choline soda)(33818-15-4) powder olupese fun opolopo odun, a ipese awọn ọja pẹlu ifigagbaga idiyele, ati pe ọja wa jẹ didara ti o ga julọ ati pe o ṣe idanwo ti o muna, idanwo ominira lati rii daju pe o jẹ ailewu fun lilo ni ayika agbaye.
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[2] Jiang JJ, Xie YM, Zhang Y, Zhang YK, Wang ZM, Han B. [Awọn abuda oogun ti iṣegun ti abẹrẹ Shuxuening ni itọju ti iwadii infarction cerebral ti o da lori iforukọsilẹ]. Zhongguo Zhong Yao Za Zhi. Ọdun 2016 Oṣu Kẹjọ; 41 (24): 4516-4520. doi: 10.4268 / cjcmm20162407. Ṣaina. PubIDed PMID: 28936832.
[3] Liu Y, Wang J, Xu C, Chen Y, Yang J, Liu D, Niu H, Jiang Y, Yang S, Ying H. Daradara iṣelọpọ iṣelọpọ ọpọ-enzymu-catalyzed CDP-choline ti a ṣakoso nipasẹ olulana ifunni ATP. Appl Microbiol Biotechnol. 2017 Oṣu keji; 101 (4): 1409-1417. doi: 10.1007 / s00253-016-7874-0. Epub 2016 Oṣu Kẹwa 13. PubMed PMID: 27738720.
[4] Giménez R, Raïch J, Aguilar J (Oṣu kọkanla 1991). "Awọn iyipada ninu ọpọlọ striatum dopamine ati awọn olugba acetylcholine ti a fa nipasẹ itọju CDP-choline onibaje ti awọn eku ti ogbo". Iwe akọọlẹ ti British Journal of Pharmacology. 104 (3): 575-8. ṣe: 1111 / j.1476-5381.1991.tb12471.x. PMC1908237. PMID1839138.
[5] Tardner, P. (2020-08-30). “Lilo ti citicoline fun itọju idinku imọ ati ailagbara ọgbọn: Ayẹwo-meta ti awọn iwe-oogun nipa oogun • Iwe Iroyin International ti Imọ Ayika & Ọna ẹrọ”. Iwe Iroyin kariaye ti Imọ Ayika & Imọ-ẹrọ. Ti gba wọle 2020-08-31.
