Iṣuu soda Citicoline (33818-15-4)

O le 8, 2021

Cofttek jẹ iṣelọpọ Citicoline Sodium (CDP Choline Sodium) ti iṣelọpọ lulú ni Ilu China. Ile -iṣẹ wa ni eto iṣakoso iṣelọpọ pipe (ISO9001 & ISO14001), pẹlu agbara iṣelọpọ oṣooṣu ti 220kg.

 


ipo: Ni Ifilelẹ Production
Apapọ: 1kg / apo, 25kg / Ilu

Iṣuu soda Citicoline (CDP Choline soda)(33818-15-4) Sawọn ilana

Name: Iṣuu soda Citicoline (CDP Choline soda)
CAS: 33818-15-4
ti nw 98%
Agbekalẹ molula C14H25N4NaO11P2
Iwuwo molula: 510.308 g / mol
Orisun Isanmi: > 240 ° C
Orukọ kemikali: Sodium Citicoline; Iṣuu soda Cdp-choline
Synonyms: Sodium [[(2S,3R,4S,5S)-5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-oxidophosphoryl]2-(trimethylazaniumyl)ethyl phosphate
InChI Key: YWAFNFGRBBSPD-KDVMHAGBSA-M
Igbesi aye Aitẹnilọrun: 56 wakati
Solubility: Wahala ni DMSO, Omi (Kekere)
Ipo Ibi ipamọ: Gbẹ, okunkun ati ni 0 - 4 C fun igba kukuru (awọn ọjọ si awọn ọsẹ) tabi -20 C fun igba pipẹ (awọn oṣu si ọdun).
ohun elo: Iṣuu soda Citicoline jẹ oluranlowo neuroprotective ati afikun ijẹẹmu
irisi: Funfun ti o mọ dulú

 

Sodium Citicoline (33818-15-4) NMR julọ.Oniranran

Iṣuu soda Citicoline (33818-15-4) Iwoye NMR

Ti o ba nilo COA, MSDS, HNMR fun ipele kọọkan ti ọja ati alaye miiran, jọwọ kan si wa alakoso tita.

 

ohun ti o jẹ Iṣuu soda Citicoline (CDP Choline soda)(33818-15-4) ?

Iṣuu Sodium Citicoline (CDP-choline Sodium, cytidine 5a-diphosphocholine) lulú jẹ eroja tiotuka omi eyiti o jẹ iṣaaju si choline mejeeji ati cytidine laarin ọpọlọ (eyiti o yipada nigbamii si uridine). Si awọn eniyan, Citicoline Iṣuu jẹ eroja pataki bi ipa rẹ ninu idinku awọn abawọn tube ti ko nira, arun ẹdọ ọra, ati awọn pathologies miiran ti ni akọsilẹ. CDP-choline Sodium jẹ ọkan ninu awọn phospholipids ti o ni choline mẹta ti o le ṣe afikun ọrọ ni ẹnu (awọn meji miiran jẹ alpha-GPC ati phosphatidylcholine).

 

Iṣuu soda Citicoline (CDP Choline soda)(33818-15-4) anfani

CDP-choline n mu biosynthesis ti iṣelọpọ phospholipids ṣiṣẹ ninu awọn membranes ti iṣan, mu iṣelọpọ ti ọpọlọ pọ si ati awọn iṣe lori awọn ipele ti ọpọlọpọ awọn neurotransmitters. Nitorinaa, a ti fihan rẹ ni aṣeyẹwo pe CDP-choline n mu noradrenaline ati awọn ipele dopamine pọ si ni CNS.

Atunṣe afikun yii ni a ṣe itọju si idilọwọ tabi ṣe itọju awọn ailera aifọwọyi ti o ni nkan ṣe pẹlu ogbologbo nitori otitọ pe awọn aami meji ti o ṣafihan jẹ neuroprotective ati ki o le ṣe afihan ikẹkọ. Bi o ṣe dabi pe o ni iṣe ti o munadoko diẹ sii ju phosphatidylcholine (PC) ni ipa yii, ni apakan nitori tun npọ sii PC kaakiri ninu ọpọlọ, agbara rẹ jẹ eyiti o ṣe afiwe si ti Alpha-GPC.

 

Iṣuu soda Citicoline (CDP Choline soda)(33818-15-4) ipawo

CDP-choline ni diẹ ninu awọn lilo agbara miiran ni ibatan si idanimọ. O ti lo ni igbagbogbo bi imudara iranti ni ọdọ, ṣugbọn pelu diẹ ninu awọn iwadii ti o daba pe eyi ṣee ṣe pẹlu CDP-choline ti ẹnu, ko si awọn ẹkọ eniyan ni ọdọ ni aaye yii ni akoko. Iwadii kan ti ṣe akiyesi ilosoke ninu ifojusi pẹlu iwọn kekere CDP-choline (eyiti o nilo lati tun ṣe), ati CDP-choline le ni awọn ipa bi ẹya egboogi-afẹsodi ti o lodi si kokeni mejeeji ati (ẹri akọkọ ti o daba) ounjẹ bakanna ..

 

Iṣuu soda Citicoline (CDP Choline soda)(33818-15-4) ohun elo

Citicoline Sodium (CDP Choline Sodium) lulú jẹ oluranlowo neuroprotective. O n ṣiṣẹ nipa gbigbe ibaraẹnisọrọ sẹẹli pọ si, iwuri idapọ ti SAMe, ati jijẹ iṣelọpọ ti glucose pọ si. Iṣu lulú Citicoline Sodium (CDP Choline Sodium) lulú jẹ nucleotide ti n ṣẹlẹ nipa ti ara; agbedemeji ni ipa-ọna akọkọ ti lecitin biosynthesis. Neuroprotective. O ti lo ninu itọju ikọlu iṣan ara ati ibalokanjẹ ori. Neuroprotective ọja. Citicholine ṣe afihan awọn ipa aabo ni ischemia ti ọpọlọ, ọgbẹ ọpọlọ, ati awọn rudurudu iranti. Laipe fihan ipa lodi si iyawere nigbati a ba fun pẹlu AchEIs (Onidena Acetylcholinesterase). N ṣe afihan Neuroprotective, iṣẹ acnticonvulsant ati ipa imukuro ni iwọn lilo 150mg / kg ninu awọn eku. Afihan ti a fihan lodi si aiṣedede imoye ti a fa ni aluminiomu ninu awọn eku idinku ipele giluteni ti o ga, atẹgun atẹgun ati KO ṣe agbejade pupọ ni hippocampus.

 

Iṣuu soda Citicoline (CDP Choline soda)(33818-15-4) lulú fun sale

(Nibo ni lati Ra Iṣuu Citicoline (CDP Choline soda)(33818-15-4) lulú ni olopobo)

Ile-iṣẹ wa gbadun awọn ibatan igba pipẹ pẹlu awọn alabara wa nitori a fojusi iṣẹ iṣẹ alabara ati pese awọn ọja nla. Ti o ba nifẹ si ọja wa, a rọ pẹlu isọdi ti awọn aṣẹ lati baamu iwulo rẹ pato ati akoko akoko iyara wa lori awọn iṣeduro awọn iṣeduro iwọ yoo ni itọwo ọja wa ni akoko gidi. A tun idojukọ lori awọn iṣẹ kun-iye. A wa fun awọn ibeere iṣẹ ati alaye lati ṣe atilẹyin iṣowo rẹ.

A jẹ ọjọgbọn kan Iṣuu soda Citicoline (CDP Choline soda)(33818-15-4) oluta lulú fun ọdun pupọ, a pese awọn ọja pẹlu idiyele ifigagbaga, ati pe ọja wa jẹ ti didara ti o ga julọ ati pe o nira, idanwo ominira lati rii daju pe o jẹ ailewu fun agbara ni ayika agbaye.

 

jo

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[2] Jiang JJ, Xie YM, Zhang Y, Zhang YK, Wang ZM, Han B. [Awọn abuda oogun ti iṣegun ti abẹrẹ Shuxuening ni itọju ti iwadii infarction cerebral ti o da lori iforukọsilẹ]. Zhongguo Zhong Yao Za Zhi. Ọdun 2016 Oṣu Kẹjọ; 41 (24): 4516-4520. doi: 10.4268 / cjcmm20162407. Ṣaina. PubIDed PMID: 28936832.

[3] Liu Y, Wang J, Xu C, Chen Y, Yang J, Liu D, Niu H, Jiang Y, Yang S, Ying H. Daradara iṣelọpọ iṣelọpọ ọpọ-enzymu-catalyzed CDP-choline ti a ṣakoso nipasẹ olulana ifunni ATP. Appl Microbiol Biotechnol. 2017 Oṣu keji; 101 (4): 1409-1417. doi: 10.1007 / s00253-016-7874-0. Epub 2016 Oṣu Kẹwa 13. PubMed PMID: 27738720.

[4] Giménez R, Raïch J, Aguilar J (Oṣu kọkanla 1991). "Awọn iyipada ninu ọpọlọ striatum dopamine ati awọn olugba acetylcholine ti a fa nipasẹ itọju CDP-choline onibaje ti awọn eku ti ogbo". Iwe akọọlẹ ti British Journal of Pharmacology. 104 (3): 575-8. ṣe: 1111 / j.1476-5381.1991.tb12471.x. PMC1908237PMID1839138.

[5] Tardner, P. (2020-08-30). “Lilo ti citicoline fun itọju idinku imọ ati ailagbara ọgbọn: Ayẹwo-meta ti awọn iwe-oogun nipa oogun • Iwe Iroyin International ti Imọ Ayika & Ọna ẹrọ”. Iwe Iroyin kariaye ti Imọ Ayika & Imọ-ẹrọ. Ti gba wọle 2020-08-31.