Acid Lipoic Acid (ALA) (1077-28-7) Sawọn ilana
| Name: | Acid Alpha Lipoic (ALA) |
| CAS: | 1077-28-7 |
| ti nw | 98% |
| Agbekalẹ molula | C8H14O2S2 |
| Iwuwo molula: | 206.33 g / mol |
| Orisun Isanmi: | 60 – 62 ° C (140 – 144 ° F; 333 – 335 K) |
| Orukọ kemikali: | (R) -5- (1,2-Dithiolan-3-yl) pentanoic acid;
acid-Lipoic acid; Alpha lipoic acid; Thioctic acid; 6,8-Dithiooctanoic acid |
| Synonyms: | (±) -α-Lipoic acid, (±) -1,2-Dithiolane-3-pentanoic acid, 6,8-Dithiooctanoic acid, DL -α-Lipoic acid, DL -6,8-Thioctic acid, Lip (S2) ) |
| InChI Key: | AGBQKNBQESQNJD-UHFFFAOYSA-N |
| Igbesi aye Aitẹnilọrun: | Igbesi aye idaji ti ọrọ ti a nṣakoso ni ALA jẹ 30 iṣẹju |
| Solubility: | O Tutu pupọ Ni omi (0.24 g / L); Solubility ni ethanol 50 mg / milimita |
| Ipo Ibi ipamọ: | 0 - 4 C fun igba kukuru (awọn ọjọ si awọn ọsẹ), tabi -20 C fun igba pipẹ (awọn oṣu) |
| ohun elo: | A lo Alpha-lipoic acid ninu ara lati fọ awọn carbohydrates lulẹ ati lati ṣe agbara fun awọn ara miiran ninu ara. Alpha-lipoic acid dabi pe o ṣiṣẹ bi ẹda ara ẹni, eyiti o tumọ si pe o le pese aabo fun ọpọlọ labẹ awọn ipo ibajẹ tabi ipalara. |
| irisi: | Awọn kirisita ti o dabi abẹrẹ Yellow |
Acid Lipoic Acid (ALA) (1077-28-7) NMR julọ.Oniranran
Ti o ba nilo COA, MSDS, HNMR fun ipele kọọkan ti ọja ati alaye miiran, jọwọ kan si wa alakoso tita.
Acid Alpha Lipoic (ALA) (1077-28-7)?
Alpha-lipoic acid jẹ apopọ ti a rii nipa ti inu gbogbo sẹẹli ti ara eniyan. Iṣe akọkọ rẹ ni lati yi gaari suga (glucose) pada si agbara nipa lilo atẹgun, ilana ti a tọka si bi iṣelọpọ eerobic. A tun ka Alpha-lipoic acid ni ẹda ara ẹni, itumo pe o le yomi awọn agbo ogun ti o ni ipalara ti a pe ni awọn ipilẹṣẹ ọfẹ ti o ba awọn sẹẹli bajẹ ni ipele jiini.
Kini o ṣe ki alpha-lipoic acid jẹ alailẹgbẹ ni pe o jẹ tiotuka ninu omi mejeeji ati ọra. Iyẹn tumọ si pe o le fi agbara ranṣẹ lẹsẹkẹsẹ tabi tọju rẹ fun lilo ọjọ iwaju.
Alfa-lipoic acid tun le tunlo awọn antioxidants “ti a lo”, pẹlu Vitamin C, Vitamin E, ati agbara amino acid ti o lagbara ti a mọ ni glutathione.1 Nigbakugba ti awọn antioxidants wọnyi ba yomi ipilẹ ti ominira kan, wọn ṣe iparun ati di awọn ipilẹṣẹ ọfẹ funrara wọn. Alpha-lipoic acid ṣe iranlọwọ lati mu wọn pada nipa gbigbe awọn elekitironi ti o pọ julọ ati yi wọn pada si ẹhin si fọọmu iduroṣinṣin wọn.
Alfa-lipoic acid ni igbagbogbo mu bi afikun labẹ iṣaro o le mu awọn iṣẹ ti iṣelọpọ dara si, pẹlu sisun ọra, iṣelọpọ collagen, ati iṣakoso glukosi ẹjẹ. Ẹri dagba wa ni o kere diẹ ninu awọn ẹtọ wọnyi.
Alpha Lipoic Acid (ALA) (1077-28-7) awọn anfani
àtọgbẹ
O ti ni igbagbogbo pe acid alpha-lipoic le ṣe iranlọwọ ninu iṣakoso glukosi nipasẹ jijẹ iyara ninu eyiti a mu ida suga ẹjẹ pọ. Eyi le ṣe iranlọwọ ni itọju ninu itọju àtọgbẹ, aisan kan ti o ni awọn ipele glukosi ẹjẹ giga ti ko ni ajeji.
Atunyẹwo eto igbekalẹ 2018 ati igbekale meta ti awọn idanwo idanimọ ti 20 ti awọn eniyan ti o ni awọn rudurudu ti iṣelọpọ (diẹ ninu wọn ni iru àtọgbẹ 2, awọn miiran ni awọn rudurudu ti iṣelọpọ miiran) ri pe afikun lipoic acid dinku glukosi ẹjẹ ti o yara, ifọkansi insulini, itọju insulin, ati ẹjẹ pupa Awọn ipele A1C.
Irora Nerve
Neuropathy jẹ ọrọ iṣoogun ti a lo lati ṣe apejuwe irora, numbness, ati awọn aiṣedede ajeji ti o fa nipasẹ ibajẹ ara. Nigbagbogbo, ibajẹ naa jẹ nipasẹ aapọn ipanilara ti a gbe sori awọn ara nipasẹ awọn aisan onibaje gẹgẹbi àtọgbẹ, arun Lyme, shingles, arun tairodu, ikuna akọn, ati HIV.
O gba nipasẹ diẹ ninu awọn pe alpha-lipoic acid, ti a fun ni awọn abere to tobi, le dojuko wahala yii nipa ṣiṣe iṣẹ apakokoro agbara. Ẹri ti wa ti ipa yii ni awọn eniyan ti o ni neuropathy dayabetik, ipo ailera ti o le ni iriri ninu awọn eniyan ti o ni àtọgbẹ to ti ni ilọsiwaju.
Atunyẹwo 2012 ti awọn ẹkọ lati Fiorino pari pe ojoojumọ 600-mg iṣọn inu iṣọn-ara ti alpha-lipoic acid ti a fun ni ọsẹ mẹta ti pese "idinku pataki ati iwosan ni irora neuropathic."
As with the previous diabetes studies, oral alpha-lipoic acid awọn afikun were generally less effective or had no effect at all.
Alpha-lipoic acid’s ability to enhance calorie burning and promote àdánù làìpẹ has been exaggerated by many diet gurus and supplements manufacturers. With that being said, there is growing evidence that alpha-lipoic acid can influence weight, albeit modestly.
A 2017 review of studies from the Yale University found that alpha-lipoic acid supplements, ranging in dose from 300 to 1,800 mg daily, helped prompt an average àdánù làìpẹ of 2.8 pounds compared to a placebo.
There was no association between the alpha-lipoic supplement dose and the amount of àdánù làìpẹ. Moreover, the duration of treatment appears to influence a person’s body mass index (BMI), but not the person’s actual weight.
Ohun ti eyi tumọ si ni pe, lakoko ti o han pe o le padanu iwuwo pupọ pẹlu alpha-lipoic acid, akopọ ara rẹ le ni ilọsiwaju bi a ti rọpo ọra ni rọra nipasẹ iṣan titẹ.
ga idaabobo awọ
A ti gba Alpha-lipoic acid ni pipẹ lati ni ipa iwuwo ati ilera nipa yiyipada akopọ ọra (ọra) ninu ẹjẹ. Eyi pẹlu jijẹ idaabobo awọ “ti o dara” ti iwuwo giga (HDL) pọsi lakoko ti o dinku idaabobo awọ “buburu” iwuwo kekere-iwuwo kekere (LDL) ati awọn triglycerides. Iwadi laipe yi daba pe eyi le ma ri bẹ.
Ninu iwadi 2011 lati Koria, awọn agbalagba 180 pese 1,200 si 1,800 mg ti alpha-lipoic acid padanu 21 ida diẹ sii ju iwuwo ibi-aye lọ lẹhin awọn ọsẹ 20 ṣugbọn ko ni iriri awọn ilọsiwaju ni apapọ idaabobo awọ, LDL, HDL, tabi awọn triglycerides.
Ni otitọ, awọn abere ti o ga julọ ti alpha-lipoic acid ni fifun si awọn alekun ni apapọ idaabobo awọ ati LDL ninu awọn olukopa iwadi.
Awọ-ti bajẹ Sun
Cosmetics manufacturers often like to boast that their awọn ọja benefit from the “anti-aging” properties of alpha-lipoic acid. Research suggests that there may some credence to these claims. A review article notes that it is a powerful antioxidant and has been studied for its protective effects against radiation damage.
Acid Lipoic Acid (ALA) (1077-28-7) ipawo?
Alpha-lipoic acid or ALA is a naturally occurring compound that’s made in the body. It serves vital functions at the cellular level, such as energy production. As long as you’re healthy, the body can produce all the ALA it needs for these purposes. Despite that fact, there has been a lot of recent interest in using ALA supplements. Advocates of ALA make claims that range from beneficial effects for treating conditions such as diabetes and HIV to enhancing àdánù làìpẹ.
Acid Lipoic Acid (ALA) (1077-28-7) doseji
Lakoko ti a ṣe akiyesi ailewu, ko si awọn itọnisọna ti o ṣe itọsọna lilo deede ti alpha-lipoic acid. Ọpọlọpọ awọn afikun ẹnu ni a ta ni awọn agbekalẹ ti o wa lati 100 si 600 miligiramu. Da lori ọpọlọpọ ti ẹri lọwọlọwọ, iwọn lilo ojoojumọ ti o to 1,800 iwon miligiramu ni a gba pe o ni aabo ni awọn agbalagba.
Pẹlu eyi ti a sọ, ohun gbogbo lati iwuwo ara ati ọjọ ori si iṣẹ ẹdọ ati iṣẹ kidinrin le ni ipa ohun ti o jẹ ailewu fun ọ bi ẹni kọọkan. Gẹgẹbi ofin atanpako gbogbogbo, ṣe aṣiṣe ni ẹgbẹ ti iṣọra ati nigbagbogbo yọkuro fun iwọn lilo kekere.
Alpha lipoic acid supplements can be found online and in many health food stores and drugstores. For maximum absorption, the supplements should be taken on an empty stomach.
Alpha-lipoic Acid lulú fun sale(Nibo ni lati Ra Alpha-lipoic Acid lulú ni olopobobo)
Ile-iṣẹ wa gbadun awọn ibatan igba pipẹ pẹlu awọn alabara wa nitori a dojukọ alabara iṣẹ ati pese awọn ọja nla. Ti o ba nifẹ si ọja wa, a ni irọrun pẹlu isọdi ti awọn ibere lati ba iwulo rẹ pato ati akoko itọsọna iyara wa lori awọn iṣeduro awọn iṣeduro pe iwọ yoo ni itọwo nla ọja wa ni akoko. A tun ṣe idojukọ awọn iṣẹ ti a fi kun iye. A wa fun awọn ibeere iṣẹ ati alaye lati ṣe atilẹyin iṣowo rẹ.
We are an professional Alpha-lipoic Acid powder olupese fun awọn ọdun pupọ, a pese awọn ọja pẹlu idiyele ifigagbaga, ati pe ọja wa jẹ didara ti o ga julọ ati pe o ni idanwo ti o muna, idanwo ominira lati rii daju pe o jẹ ailewu fun lilo ni ayika agbaye.
jo
- Haenen, GRMM; Bast, A (1991). “Scavecing ti hypochlorous acid nipasẹ lipoic acid”. Ẹkọ nipa Oogun. 42 (11): 2244-6. ṣe: 10.1016 / 0006-2952 (91) 90363-A. PMID 1659823.
- Biewenga, GP; Haenen, GR; Bast, A (Oṣu Kẹsan 1997). "Ẹkọ nipa oogun ti antioxidant lipoic acid". Gbogbogbo Oogun. 29 (3): 315–31. ṣe: 10.1016 / S0306-3623 (96) 00474-0. PMID 9378235.
- Schupke, H; Hempel, R; Peteru, G; Hermann, R; et al. (Okudu 2001). “Awọn ipa ọna iṣelọpọ titun ti alpha-lipoic acid”. Iṣelọpọ Oogun ati Ifi silẹ. 29 (6): 855-62. PMID 11353754.
- Acker, DS; Wayne, WJ (1957). “Ṣiṣẹ Optical ati ipanilara α-lipoic acids”. Iwe akosile ti American Chemical Society. 79 (24): 6483–6487. ṣe: 10.1021 / ja01581a033.
- Hornberger, CS; Heitmiller, RF; Gunsalus, IC; Schnakenberg, GHF; et al. (1952). "Igbaradi sintetiki ti lipoic acid". Iwe akosile ti American Chemical Society. 74 (9): 2382. doi: 10.1021 / ja01129a511.
